Dr. Abdul deem G.M. Al-Selwi
Mohammed V University, Moroccco
Abstract Title: Study of antibiotic resistance in the neonatology department of the Ibn Sina University Hospital in Rabat, Morocco.
Biography:
Dr. Abdul deem G.M. Al-Selwi completed his Ph.D. in Clinical Epidemiology and Surgical Sciences from Mohammed V University, Faculty of Medicine and Pharmacy, Rabat, Morocco, and pursued postdoctoral studies focused on maternal and newborn health research. He is the Executive Director of the ARWQA Center for Studies, Translation, and Publishing, a leading institution renowned for its academic programs and scientific contributions throughout the Arab region. Dr. Selwi has authored numerous peer-reviewed research papers, contributed to global health programs in more than 17 countries, and is a member of several scientific editorial and review committees.
Research Interest:
Nosocomial infections are a serious public health problem, leading to high rates of morbidity and mortality as well as high expenditures. Objective: To describe the prevalence and characteristics of nosocomial neonatal bacterial infections and their resistance to antibiotics in a group of Moroccan newborns. Material and methods: We included hospitalized neonates managed for nosocomial bacterial infections over a period from March 1 to June 31, 2022. Results: The incidence rate of healthcare-associated infections during the study period was 18.7%, and the incidence density was 10 cases/1000 DH. The results show a predominance of males (65.67%), most hospitalized within the first 24 hours (82.08%), with a significant proportion of low-weight newborns (61.19%). The reasons for hospitalization were respiratory distress (71.64%), perinatal asphyxia (26.86%), neonatal bacterial infections (16.41%), prematurity (16.41%), and esophageal atresia (14.92%). Concerning the resistance and sensitivity of germs in nosocomial infections to TBAs: coagulase-positive Staphylococcus showed high rates of resistance to antibiotics, particularly gentamicin (96%), teicoplanin (96%) and amoxicillin (76%). However, it remains sensitive to vancomycin (100%). Enterobacter cloacae showed 100% resistance to ampicillin, Piperacillin/Tazobactam, Ceftriaxone, Ceftazidime, and Ciprofloxacin, and 50% to gentamicin, erythromycin, Meropenem, Cefoxitin, Trimethoprim/sulfamethoxazole and imipenem. Acinetobacter baumannii showed 100% resistance to amoxicillin and gentamicin, and 88% to ciprofloxacin and imipenem. Escherichia coli showed total resistance to ampicillin, amoxicillin/clavulanic acid, and trimethoprim/sulfamethoxazole, 85.7% to ceftazidime and 71.4% to gentamicin and ceftriaxone. Klebsiella pneumonia was 100% resistant to gentamicin and 87.5% to several TBAs, including ampicillin. The outcome was favorable in 67.16% of cases.